The context in which opioids are taken can impact tolerance for their effects Shutterstock/mwesselsphotography
A newly discovered brain pathway in mice may contribute to the development of opioid tolerance, suggesting that future therapies targeting this pathway could prevent opioid addiction and overdose.
Opioids like morphine, oxycodone and fentanyl are effective painkillers, but also highly addictive as frequent use necessitates increasingly larger doses to achieve the same effect. This raises the risk of overdose, which is a growing problem in the US: in 2020, nearly 69,000 people died from opioid …
